Does Clopidogrel Cause Joint Pain?

Which is better aspirin or clopidogrel?

Clopidogrel is another guideline‐recommended antiplatelet agent21 and has been shown to be superior to aspirin in preventing composite vascular events and reducing hemorrhagic complications in a randomized controlled trial, CAPRIE (Clopidogrel versus Aspirin in Patients at Risk of Ischaemic Events)..

Is clopidogrel an anti inflammatory?

Clopidogrel (CLO) is structurally a thienopyridine derivative and specifically inhibits ADP-dependent platelet aggregation and adhesion via inhibition of the purinergic P2Y12 receptor. It was reported recently that clopidogrel has a property of anti-inflammation.

What is the best time to take clopidogrel?

You can take clopidogrel at whatever time of day you find easiest to remember, but take your doses at the same time of day each day. Most people prefer to take it in the morning, as they find this helps them to remember to take it regularly. You can take the tablet either before or after a meal.

Why do all my joints hurt suddenly?

Key Points. Acute pain in multiple joints is most often due to inflammation, gout, or the beginning or flare up of a chronic joint disorder. Chronic pain in multiple joints is usually due to osteoarthritis or an inflammatory disorder (such as rheumatoid arthritis) or, in children, juvenile idiopathic arthritis.

Does clopidogrel affect the liver?

The severity of liver injury associated with clopidogrel ranges from transient, mild serum enzyme elevations to clinically apparent acute hepatitis that can be severe and lead to death. Most cases resolve with drug withdrawal within 1 to 3 months.

Can you ever stop taking blood thinners?

“With this rule we can confidently tell half of the women we see that they are at low risk of having another blood clot. This means they can stop taking blood thinners once their initial clot is treated, sparing them the cost, inconvenience and risks of taking life-long medication.”

What does clopidogrel do to your body?

Clopidogrel slows the blood’s clotting action by making platelets less sticky. Platelets are blood cells that stick together to block cuts and breaks in blood vessels. But in people at risk of heart attack or stroke, platelets can stick together inside already narrowed blood vessels to form a clot.

Is it OK to take clopidogrel every other day?

Conclusions: Long term dual anti-platelet therapy with aspirin 81 mg daily and clopidogrel 75 mg every other day beyond 12 months after PCI with DES may be a safe and efficacious cost-saving strategy to prevent VLST.

What medications can make your joints hurt?

10 Common Medications That Cause Joint Pain, From Cholesterol Drugs to Asthma Inhalers1) Antibiotic — levofloxacin. … 2) Cholesterol-lowering medications — statins. … 3) Osteoporosis medication — risedronate. … 4) Asthma inhaler — fluticasone. … 5) Breast cancer medications — anastrozole, exemestane, letrozole.

What foods should you avoid if you are on blood thinners?

If you take medicine for your heart, doctors recommend staying away from some foods because of the risk of interaction….Blood thinners: Eat fewer foods with vitamin KAsparagus.Broccoli.Brussels sprouts.Cauliflower.Green onions.Kale.Parsley.Spinach.

Does clopidogrel affect blood pressure?

Arterial hypertension is associated with platelet activation, increased sCD40L levels and endothelial dysfunction suggesting that inhibition of platelet-derived sCD40L release may improve endothelial function and lower blood pressure (BP).

Is there an alternative to clopidogrel?

1). Besides oral anticoagulants, such as warfarin and the more recent dabigatran[9], and niche agents, such as cilostazol and ticlopidine[10,11], the most promising alternatives to clopidogrel in those with background aspirin therapy are prasugrel and ticagrelor.

What painkillers can I take with clopidogrel?

Painkillers. It’s fine to take paracetamol with clopidogrel. You can also take opioid-type painkillers such as codeine, co-codamol, tramadol or morphine alongside clopidogrel.

What are the most common side effects of clopidogrel?

Common side effects of clopidogrel can include:headaches or dizziness.nausea.diarrhoea or constipation.indigestion (dyspepsia)stomach ache or abdominal pain.nosebleeds.increased bleeding (your blood taking longer to clot – for example, when you cut yourself), or easy bruising.

What is the best vitamin for joint pain?

Supplements and Medications To Help Joint PainVitamin D. The number one supplement I recommend for joint health and overall musculoskeletal health is vitamin D3. … Estrogen. Estrogen is important for musculoskeletal health, including joint health. … Glucosamine and Chondroitin Sulfate. … MSM. … Turmeric. … Omega 3. … Ginger. … SAMe.

What are the 5 worst foods to eat if you have arthritis?

In the Kitchen with Arthritis: Foods to AvoidProcessed foods. Avoid processed foods, such as baked goods and prepackaged meals and snacks. … Omega-6 fatty acids. … Sugar and certain sugar alternatives. … Red meat and fried foods. … Refined carbohydrates. … Cheese and high-fat dairy. … Alcohol.

Can you take clopidogrel long term?

Safety Announcement. [ 11-06-2015 ] A U.S. Food and Drug Administration (FDA) review has determined that long-term use of the blood-thinning drug Plavix (clopidogrel) does not increase or decrease overall risk of death in patients with, or at risk for, heart disease.

Can I drink coffee with Plavix?

Conclusions. Acute caffeine administration after clopidogrel loading appears to be associated with enhanced platelet inhibition 2 to 4 hours after clopidogrel intake. The mechanism probably involves synergistic increase in cAMP levels.