What Is The Function Of The Juxtaglomerular Apparatus?

What is the major function of the Juxtaglomerular apparatus?

The juxtaglomerular apparatus functions to maintain blood pressure and to act as a quality control mechanism to ensure proper glomerular flow rate and efficient sodium reabsorption.

The urethra extends from the bladder to the surface of the body.

It consists of an epithelium-lined lumen and a smooth muscle layer..

Which structure is most important for urine concentration?

Which structure is most important for urine concentration? Capsular hydrostatic pressure is the chief force pushing water and solutes out of the blood and across the filtration membrane.

How does Juxtaglomerular apparatus regulate the kidney function?

The juxtaglomerular apparatus (JGA) is a control unit of the kidney, that regulates glomerular filtration rate (GFR) and renin release, and hence extracellular volume and blood pressure. The tubuloglomerular feedback (TGF) mechanism is a negative feedback loop that regulates GFR.

What are the functions of the macula densa quizlet?

What is the function of the macula densa cells of the juxtaglomerular complex (JGC)? The macula densa cells monitor the NaCl content of the filtrate entering the distal convoluted tubule.

What activates JGA release renin?

The juxtaglomerular cells are also stimulated to release renin by signaling from the macula densa. The macula densa senses changes in sodium delivery to the distal tubule, and responds to a drop in tubular sodium load by stimulating renin release in the juxtaglomerular cells.

What three hormones factors do the kidneys secrete into the blood?

The kidney secretes (1) renin, a key enzyme of the renin-angiotensin system (RAS) that leads to the production of a potent pressor hormone angiotensin, and produces the following hormones and humoral factors: (2) kallikreins, a group of serine pro- teases that act on blood proteins to produce a vasorelaxing peptide …

What are the main parts of the Juxtaglomerular apparatus?

The juxtaglomerular apparatus, located in the glomerular hilum, consists of a vascular component (afferent and efferent arterioles and extraglomerular mesangium) and a tubular component (macula densa).

What stimulates the secretion of renin?

The secretion of renin is stimulated by the following three factors: When a fall in arterial blood pressure is detected by pressure sensitive receptors (baroreceptors) in the arterial vessels. When a decrease in sodium chloride (salt) is detected in the kidney by the macula densa in the juxtaglomerular apparatus.

What enzyme is released by the Juxtaglomerular complex to regulate GFR?

ReninRenin is an enzyme that is produced by the granular cells of the afferent arteriole at the juxtaglomerular apparatus.

What happens during tubular reabsorption?

Tubular reabsorption is the process that moves solutes and water out of the filtrate and back into your bloodstream. This process is known as reabsorption, because this is the second time they have been absorbed; the first time being when they were absorbed into the bloodstream from the digestive tract after a meal.

Where is the Juxtaglomerular apparatus located quizlet?

Where is the Juxtaglomerular Apparatus located? In the distal tubule, specifically the region that passes between the afferent & efferent arterioles. Tubuloglomerular feedback about the sodium & chloride composition in the distal tubule affects arteriolar tone.

What is the Juxtamedullary nephron?

In other words, a juxtamedullary nephron is a nephron whose renal corpuscle is near the medulla, and whose proximal convoluted tubule and its associated loop of Henle occur deeper in the medulla than the other type of nephron, the cortical nephron.

What do macula densa cells secrete?

Macula densa cells in the distal nephron, according to the classic paradigm, are salt sensors that generate paracrine chemical signals in the juxtaglomerular apparatus to control vital kidney functions, including renal blood flow, glomerular filtration, and renin release.

What hormone is secreted by the juxtaglomerular apparatus?

ReninRenin is produced by juxtaglomerular cells. These cells are similar to epithelium and are located in the tunica media of the afferent arterioles as they enter the glomeruli. The juxtaglomerular cells secrete renin in response to: Stimulation of the beta-1 adrenergic receptor.

Where are Juxtaglomerular cells found?

The juxtaglomerular cells (JG cells, or granular cells) are cells in the kidney that synthesize, store, and secrete the enzyme renin. They are specialized smooth muscle cells mainly in the walls of the afferent arterioles (and some in the efferent arterioles) that deliver blood to the glomerulus.

What is the function of the Juxtaglomerular apparatus quizlet?

Macula Densa & Juxtaglomerular cells. What is the main function of the Juxtaglomerular apparatus? To secrete Erythropoitein and Renin.

What is the Juxtaglomerular apparatus?

The juxtaglomerular apparatus is the location of renin-secreting cells and the macula densa and lies at the junction between the loop of Henle and the distal nephron at which the tubule comes in close proximity to the afferent arteriole.16.

What activates Juxtaglomerular cells?

Juxtaglomerular Cells Although they are activated by prostaglandins released from the macula densa cells, they can also release renin independently of the macula densa. Baroreceptors found in the arterioles trigger renin secretion if there is a fall in blood pressure in the arterioles.